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Department of Neurobiology & Psychology
University of California, Los Angeles
dario@ucla.edu
Mesoscope recordings from mouse visual cortex using
The Ringach Lab
Local tuning biases in mouse primary visual cortex
The geometry of masking in neural populations
Examples of recent research
Neuromodulatory control of localized dendritic spiking in critical period cortex
An inhibitory push-pull circuit in frontal cortex
Active learning of cortical connectivity from two-photon imaging data
Functional clusters of neurons in layer 6 of macaque V1
State-dependent subnetworks of parvalbumin-expressing interneurons in cortex
Community-based benchmarking improves spike-based inference from two-photon imaging data
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Orientation tuning in macaque V1
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This database describes the tuning curves of 308 neurons in macaque V1 (M. fascicularis). This are the raw data for all the figures in the paper Ringach et al, “Orientation Selectivity in Macaque V1: Diversity and Laminar Dependence”. J Neurosci. 22(13):5639-5651, 2002. The variables in the file are as follows:
db.orivar: circular variance of the orientation tuning curve based on mean spike rate
db.maxdc: maximum spike rate across all orientations
db.mindc: minimum spike rate across all orientations
db.maxfirst: the first harmonic response at the optimal orientation
db.po: The ratio between the responses at the orthogonal vs preferred orientation
db.bw: Bandwidth of the tuning curve
db.spont: Spontaneous firing rate
db.depth: Normalized cortical distance (see paper for explanation)
db.animal: Animal ID
db.expt: Experiment ID
db.chan: Electrode channel
Funding: Work funded by NIH-EY12816, NSF-IBN-9720305, EY-08300, EY-01472
Spatial structure of simple cells in macaque V1
This database contains the analysis of shapes of 2D receptive fields in macaque V1 as described in Ringach, “Spatial Structure and Symmetry of Simple Cell Receptive Fields in Macaque V1" . J Neurophysiol. 88:455-463, 2002. The variables in the file are as follows:
db.nx: circular variance of the orientation tuning curve based on mean spike rate
db.ny: maximum spike rate across all orientations
db.ph: minimum spike rate across all orientations
db.animal: Animal ID
db.expt: Experiment ID
db.chan: Electrode channel
Funding: Work funded by NIH-EY12816, NSF-IBN-9720305, EY-08300, EY-01472
Overlap of ON and OFF subregions in macaque V1
This database contains the analysis of subregion overlap across 300 cells as described in Mata et al, “Spatial overlap of ON and OFF subregions and their relation to response modulation ration in macaque primary visual cortex" . J Neurophysiol. 2004. The variables in the file are as follows:
db(:,1): Discreteness measure (alpha)
db(:,2): Correlation coefficient (rho)
db(:,3): Normalized distance (delta)
db(:,4): Overlap index (omega)
db(:,5): Relative phase measure
db(:,6): F1/F0 ratio
Funding: Work funded by NIH-EY12816 and a Research to Prevent Blindness from the Jules Stein Institute
A Matlab implementation of the model described in Carandini and Ringach “Predictions of a recurrent model of orientation selectivity”, Vision Research, 1997
Model of orientation tuning
An implementation of Hartigan’s dip test for bimodality in Matlab
Hartigan’s dip test
This Matlab function implements maximum liklihood estimation of tetrachoric correlation as described in Tallis, “The maximum likelihood of correlation from contingency tables”, Biometrika, 1962.
Tetrachoric correlation
Orientation tuning in Macaque V1
Recurrent model of oreintation tuning
Some of our older data, code an algorithms can be found here. More recent data can be found in CRCNS, Figshare and the NIH repository for the Brain Research Initiative.
Overlap of ON/OFF subregions in V1
Tetrachoric correlation estimation
Data, Code and Algorithms
Spatial Structure of Simple Cells in V1
Hartigan’s dip test of bimodality